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Embryology

In the Embryology Simulation, you will perform experiments with the chicken and mouse model organisms. Will you be able to figure out why the arms of Liebenberg patients look like legs?

About This Simulation

Embryology provides evidence of relatedness between now widely divergent groups of organisms. Mutational tweaking in the embryo can have such magnified consequences in the adult, that embryo formation tends to be conserved. As a result, structures that are absent in some groups often appear in their embryonic forms and disappear by the time the adult or juvenile form is reached. For example, all vertebrate embryos, including humans, exhibit gill slits and tails at some point in their early development. These disappear in the adults of terrestrial groups, but are maintained in adult forms of aquatic groups such as fish and some amphibians. Great ape embryos, including humans, have a tail structure during their development that is lost by the time of birth.

In the Embryology simulation, you will perform experiments with the chicken and mouse model organisms. You will observe embryos in different developmental stages and use molecular biology techniques to study the limb development of vertebrates. Your goal is to identify the causes of the mysterious Liebenberg syndrome. Will you be able to figure out why the arms of Liebenberg patients look like legs?

Screenshots

Collaborators

Prof. Brian Harfe

Prof. Brian Harfe

Associate Dean, College of Liberal Arts and Sciences

University of Florida

Emma Brady

Emma Brady

Senior Instructional Designer

UF Online

Learning Objectives

  • Understanding the advantages and disadvantages of the mouse and chicken models.
  • Exploring different developmental stages and comparing them between organisms.
  • Uncovering the molecular pathway responsible for forming forelimbs or hindlimbs.

 

Techniques

  • Chicken egg windowing

 

 

Collaborator

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