Immunology: Immunoassay for detecting SARS-CoV-2 antibodies

Different patterns of antibody production are observed depending on an individual’s exposure to a pathogen. Conduct immunoassays that detect IgG and IgM in blood serum to discover the vaccination and infection status in a community exposed to SARS-CoV-2.

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  • Description
  • Features

This short, targeted simulation is adapted from the full-length Introduction to Immunology simulation. Have you ever wondered how the research institutes monitor the infection status of various diseases? How do they keep a track on SARS-CoV-2 spread in communities? During this simulation, you’ll undertake an important global health investigation. Will you become an expert in serology and add to the planet’s immunological understanding?

Become a part of the research team

Researchers from around the world collaborate to give humanity the broadest possible understanding of pathogenicity, infection rates and the changing prevalence of diseases across the world. Confirming the immunization rates and the presence of new infection cases in local communities is vital to help allocate healthcare resources to populations worldwide. Today you will become a part of that research team.

Investigate immunity using serological techniques

As a part of the team, you will be undertaking your own serological investigation and perform an enzyme-linked immunoassay on serum samples to detect the presence of IgG and IgM antibodies related to SARS-CoV-2 virus. Don’t worry, we will guide you on each step to make sure our data is reliable and can contribute to the research.

Analyze data from samples and draw conclusions

In the end, you will analyse your data and draw conclusions about the vaccination and infection status in the community. What other conclusions can you draw from your data? Do you think you help healthcare professionals better protect communities around the world?

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Different patterns of antibody production are observed depending on an individual’s exposure to a pathogen. Conduct immunoassays that detect IgG and IgM in blood serum to discover the vaccination and infection status in a community exposed to SARS-CoV-2.

Techniques in lab
Enzyme-linked immunoassay
Learning objectives

At the end of this simulation, you will be able to...

  • Explain the concept of diagnostic serology
  • Process samples through IgG and IgM detection immunoassays
  • Relate antibody detection data from samples to potential exposure and infection statuses
Simulation features

Length: 17
Accessibility mode: Available
Languages: English

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