MALDI Investigation into Doping

Time to complete course: 25 min.

Try our lab safety simulation

Discover one of 200+ learning simulations available today

About MALDI Investigation into Doping Virtual Lab Simulation

This shorter, targeted simulation is adapted from the full-length “Protein Synthesis” simulation.

Investigate doping in bicycle athletes using MALDI. In this simulation, you will collaborate with the doping agent who collects urine samples in a large bicycle race. You will learn how to test urine samples using the mass spectrometry technique MALDI. After preparing and submitting your samples, you will interpret the mass spectrometry histograms. Can you determine if an athlete has been cheating?

Introduction to the doping substance

Start your mission with a 3D animation explaining the purpose of kidneys and the effects of chronic kidney disease on the body. Learn how erythropoietin (EPO) affects the production of red blood cells. Meet the anti-doping agent to find out how athletes have been using recombinant human erythropoietin (rhEPO) to increase their production of red blood cells and enhance their performance.

Investigate doping in bike athletes

You will use mass spectrometry and investigate if there are any athletes who are using rhEPO as a doping substance. First you will prepare the athletes urine samples by adding the matrix solution. Carefully place the prepared samples on the MALDI plate before taking the sample plate into the mass spectrometer. Learn about mass spectrometry and the technique MALDI (Matrix-assisted laser desorption/ionization) with the help of quiz questions and a short video.

Interpret the mass spectrometry histograms

At the end of the lab, you will look at the mass spectrometry histograms. Compare the peaks in the positive rhEPO sample to each of the athletes’ samples. Will you be able to determine if any of the athletes are using the doping substance?

Get Started Now

Collaborate with an anti-doping agent at a bicycle race. Test athletes’ urine for a doping substance using mass spectrometry. Can you find out which athlete has been cheating?

Techniques in Lab

Mass spectrometry

Learning Objectives

  • Understand the basic principles of mass spectrometry (MALDI-TOF)
  • Prepare samples for MALDI
  • Interpret mass spectrometry histograms

Simulation Features

Length – 25 minutes
Accessibility mode – Available
Languages – English

Examples of Related Standards


No direct alignment


No direct alignment


No direct alignment

Screenshots of MALDI Investigation into Doping Virtual Lab Simulation


How it works

A million dollar lab in your browser

Perform experiments in virtual lab simulations to achieve core science learning outcomes. 

All our simulations run on laptop and desktop computers, and you can play our simulations without having to install any browser plugins.

See detailed minimum requirements here.

Hundreds of hours of science learning content

Our virtual laboratory simulations are aimed at university, college and high school level, within fields such as biology, biochemistry, genetics, biotechnology, chemistry, physics and more.

With access to our simulations, you will have hundreds of hours of engaging, high-quality learning content available to you.

Discover more Virtual Lab Simulations

We currently have 218 simulations that cover everything from biology and medicine to physics and chemistry.

Learn how you can use Labster in your science course

Take a 15 Minute “Lab Break” with a Virtual Lab Expert

Talk to one of our Virtual Lab Experts about how Labster can engage your students with our virtual labs for online, hybrid and face-to-face courses.

Lab break coffee with us

Please fill out the form below to talk with one of our Lab Experts. 

You must opt in to receive emails from Labster. You can unsubscribe at any time.
Thank you for your submission!

Sales Demo: Discover how Labster
improves student grades and learning outcomes!

Limited to 100 people

The simulation is already added to this package

Step 1: Choose your simulations

Find and select the simulations that you want to add to your course.

Step 2: Review simulation list

This is the list of simulations that will be added to your course. Click Download once you are ready.

Press the + button next to the simulations that you want to add to your list, or add all the simulations of this package by pressing “add all simulations”.


Related Simulations

No simulations added yet.
    Download the .zip file and upload it to your LMS.

    Download Common Cartridge File

    Choose your Learning Management System below:
    Generating download link. Please wait...
    Congratulations! You can now upload the .zip file into your LMS by the following these instructions:

    Simulation name

    Image container

    Learning Outcomes

    Learning outcomes container


    Techniques container

    Simulation Description

    Description container

    Are you sure you want to delete?

    Package deleted successfully

    IMPORTANT: Check the original email with instructions from your instructor to verify how you should gain access.

    Link Access

    Did you receive a link/URL to access Labster from your teacher? This is for either “Labster Direct” or “Quick Access”, and no login is required. See info below.

    School LMS

    Are you accessing Labster from your school’s LMS, such as Canvas, Blackboard, Moodle or Brightspace? Click below to read more.
    IMPORTANT: Please check your original email to confirm the correct access option.

    Labster Direct / Quick Access

    Did you receive a link/URL to access simulations through the Labster Direct or Quick Access pages? If so, no login is required. See info below.

    Your LMS

    Are you accessing Labster from your school’s LMS, such as Canvas, Blackboard, Moodle or Brightspace? Click below to read more.

    Faculty Resources

    To access the Faculty Resources page (instructors only) and review Labster simulations, please log in below.