Select Page

Monogenic Disorders Virtual Lab

Time to complete course: 60 min.Need help? Visit our Help Center.

Get Started Now

Learn about the monogenic disorder Cystic Fibrosis and its inheritance from one generation to the next.

About the Monogenic Disorders Virtual Lab Simulation

Cystic Fibrosis is a type of monogenic disorder caused by a mutation in both copies of the CFTR gene (Cystic Fibrosis Transmembrane Conductance Regulator).

Learn about Cystic Fibrosis
The CTFR gene encodes a protein that regulates the movement of chloride ions in and out of cells that produce mucus, sweat, saliva, or tears. Cystic Fibrosis is also called mucoviscidosis because patients suffer from thickened mucus. People with one mutated copy of the CFTR gene are called carriers and do not experience any symptoms.

Patients with Cystic Fibrosis
Cystic Fibrosis is the most common autosomal recessive disease among Europeans. It is characterized by allele heterogeneity, meaning that CFTR genes from many different patients with Cystic Fibrosis show different type of mutations. The most common alteration in the CFTR gene is a deletion of three nucleotides, resulting in a loss of the amino acid phenylalanine (F) at position 508 in the protein, and is hence called ΔF508.

Apply your knowledge
In the Monogenic Disorders lab, you will learn about the monogenic disorder Cystic Fibrosis and its inheritance from one generation to the next. You will also learn how a single gene mutation leads to a dysfunctional, disease-causing protein.

Will you be able to consult a young couple on the potential risk for their future children to develop Cystic Fibrosis?

Techniques In Lab

  • PCR
  • Gel electrophoresis
  • Capillary electrophoresis

Learning Objectives

At the end of this simulation, you will be able to…

  • Understand the basic concepts of inheritance
  • Build and interpret a pedigree based on family data
  • Understand genetic risk assessment and counselling
  • Understand the work of a genetics laboratory

Screenshots of Monogenic Disorders Virtual Lab Simulation

Collaborators

Dr. Anne Nørremølle

Dr. Anne Nørremølle

Department of Cellular and Molecular Medicine

University of Copenhagen

How it works

A million dollar lab in your browser

You can now perform advanced experiments to achieve core science learning outcomes. Theory and practise is connected in a novel way, and all you need is a computer/laptop and a browser!

Our simulations run even on older laptops and computers, and you will be able to play our simulations without having to install any browser plugins.

See detailed minimum requirements here.

100s of hours of science learning content

Explore many different science topics at your pace and difficulty level.

Our virtual laboratory simulations are aimed at university, college and high school level, within fields such as Biology, Biochemistry, Genetics, Biotechnology, Chemistry, Physics and many more.

With unlimited access to more than 60 different full simulations, you will have hundreds of hours of fun, innovative and high quality learning content available to you.

Study faster with the best award-winning science education tool

Learn anytime, anywhere.

Learn anytime, anywhere.

Labster is a 24/7 state-of-the-art virtual lab at your disposal. Study and learn at your own pace from anywhere.

Money back guarantee.

Money back guarantee.

Unlimited access to your own million dollar laboratory for just $19 per month. Full money back guarantee for your first paid month.

A million dollar lab on your laptop.

A million dollar lab on your laptop.

Turn your laptop into a lab-top with unlimited access to Labster’s fast-growing, immersive blended-learning experience. We offer 60+ simulations.

Trusted and used by top universities globally

What students think about Labster:

"A very innovative, immersive learning experience. It allows you to be more confident before going to the real laboratory. It's mind-blowing!"

Alice

Alice

Student Ambassador at Exeter Uni

"A great way to learn, because it can be very hard if you are just taught the theory - here you can try it yourself."

Ellie

Ellie

Student Ambassador at Exeter Uni

"More people should know about this! Some students don't really like science and this tool is amazing to get students passionate about science by making it fun and easy to learn."

Lucy

Lucy

Student Ambassador at Exeter Uni

FAQ

Frequently Asked Quesions

I'm using Labster as part of my course. Do I need to buy a subscription?

If you are enrolled in a class and instructed by your teacher to use Labster, please make sure you use the sign-up information that has been provided by your teacher. Otherwise, your they will not be able to follow your progress and achievements, and you may need to purchase a license twice.

How many simulations will I get access to?

You will get unlimited access to all our simulations. We release new simulations nearly every month, and you can always see an overview of all our simulations in our simulation catalog.

When will my account renew?

Your subscription will renew automatically each month after the free trial is over, unless you have made a single simulation purchase.

How can I cancel my subscription?

If you want to cancel your subscription, just write an email to support@labster.com stating your email account and that you want to cancel your subscription.

What are the minimum requirements for my computer?

You can find an overview of the minimum requirements here.

Explore Other Virtual Lab Simulations

Warning: You may already have access

x
It appears that you are from an institution which already has a license agreement with us. If Labster is a requirement for your course, please visit this page (https://help.labster.com/student-access-and-guide) for further instructions. Please note that all activity and scores will not be reported to your instructor if you sign up here. If you have any questions please contact us at support@labster.com.

Already logged in

x
It appears that you are already logged in to your Labster account.
Would you like to go to your course overview to access your simulations? Go to My Course Dashboard Proceed to Trial Signup

Pin It on Pinterest