Join Kim in the Polymer Research Lab to solve the puzzle of unexpected side product formation in their optimized cyclohexanol elimination reaction. Use and expand your organic chemistry knowledge to do this and get the polymer production back on track.
University / College
Eliminate the leaving group and get double-bonded! In this simulation, you will learn the ins and outs of Elimination Reactions in Organic Chemistry. You will get hands-on experience with some alkyl halides and discover how they go through the E1 and E2 eliminations.
Polymer production going sideways
Meet Kim: a research scientist at a polymer research and production lab. They are having problems with optimizing their elimination reaction that converts cyclohexanol to cyclohexene, and they need your help to understand what’s going on and how to get it right. You will need to understand the core concepts of elimination reactions to be able to help her out!
Eliminating the unknowns
Back in the main lab, you will brush up on your organic chemistry know-how. After understanding Kim's reaction a little better, you will dive into the two main types of elimination reaction: the E1 and E2. You will be able to hands-on manipulate molecules to go through the mechanisms of the two reactions, before being challenged to figure out Zaitsev’s rule through an explorative and interactive exercise. You will also need to assess what reactants are more likely to go through the two reactions. If you get this, you might get the rockstar achievement!
Back on track
To get to the bottom of Kim’s production puzzle, you will have to carefully work out the mechanisms of the two reactions and what determines their reactivity and the products they form. Will you be able to help her solve it, so her research lab can continue producing polymers for the world?
Length:
27
mins
Accessibility mode:
Available
Languages:
English (United States)
Spanish
French
Italian
German
Course Packages:
At the end of this simulation, you will be able to:
Explain the reaction mechanisms of the E1 and E2 reactions
Compare the reactivity of different alkyl halides towards E1 and E2
Predict the product of an Elimination Reaction using Zaitsev’s rule
Predict the double-bond stereochemistry of the product in an E2 reaction
At the end of this simulation, you will be able to:
University
NGSS
IB
AP
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Explain the reaction mechanisms of the E1 and E2 reactions
Compare the reactivity of different alkyl halides towards E1 and E2
Predict the product of an Elimination Reaction using Zaitsev’s rule
Predict the double-bond stereochemistry of the product in an E2 reaction