Discover the structure and function of cell membranes by launching cargo molecules at a virtual cell. Apply your learning back in the lab to improve the health of synthetic cells that the lead researcher wants to use to produce insulin.
High School
University / College
Join Dr. B.I.O. Hacker in her synthetic biology lab, where she wants to change the world! In this simulation, you will learn about the structure and function of the cell membrane and discover why membrane transporters are vital for healthy cells and the function of organ systems.
The synthetic biology lab
Your mission begins in the synthetic biology lab. Here you will meet Dr. Hacker, who will introduce you to the concept of selective permeability and the fluid mosaic models of the plasma membrane. Together, you will explore why cells need specialized transporter proteins to transport cargo molecules across their membranes.
Transport molecules into a virtual cell
Next, you will teleport to a virtual cell, where you will explore how different types of molecules can cross the cell membrane. While some molecules are able to diffuse across the cell membrane, most molecules require a transporter protein to enter or leave the cell. Explore the different channels, carriers, and pumps that exist in the membrane and how they ensure that only the right molecules enter under the right conditions.
Apply your knowledge
Return to the lab to test whether inserting a transporter protein in the membrane would help certain molecules to enter the cell. To do so, you will set up a fluorescence microscopy experiment to measure transport in living cells. Finally, discover how some transporter proteins do not only keep the cell healthy but also help organ systems to function. From filtration in the kidneys to the contraction of muscles during exercise, membrane transport contributes to many processes. Can you find out how?
Length:
25
mins
Accessibility mode:
Available
Languages:
German
Spanish
French
Italian
English (United States)
At the end of this simulation, you will be able to:
Describe the plasma membrane structure using the fluid mosaic model
Recognize the relative permeability of lipid bilayers to different classes of molecules
Compare active and passive transport of molecules
Identify the 3 modes of active transport and the different classes of ion channel and carrier molecules
Relate the expression of specific transport proteins to the cell's role
At the end of this simulation, you will be able to:
University
NGSS
IB
AP
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