Cellular Respiration (Principles): Measure energy consumption during exercise

Help local basketball players understand how the food they eat gets converted to energy through cellular respiration. Use a mouse model to find out what effect exercise intensity has on oxygen and glucose consumption.

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About This Simulation

What does it mean to work up an appetite? In this simulation, you will learn how humans metabolize glucose through aerobic and anaerobic respiration. You will learn about the three stages of cellular respiration: glycolysis, the Krebs cycle and the electron transport chain.

Evaluate cellular respiration through exercise

You will begin by outlining the different stages of cellular respiration and study how they relate to the cell and its organelles.Then you will identify the important products of glycolysis, the Krebs cycle and the electron transport chain. As you follow the process, you will see how the cell’s main energy carrier, ATP, is produced from glucose. Finally, you will apply what you have learned about cellular respiration in a number of experiments where you will find out what effect exercise intensity has on oxygen and glucose consumption using a mouse model.

Respirometry and blood sample analysis

Next, you will measure cellular respiration by analyzing the blood glucose and lactic acid concentrations of basketball players during a game. This data will be compared to experimental exercise data collected using a mouse model and respirometry.

The experimental portion of this simulation is supplemented by an overview of the central steps of glycolysis, phosphorylation and the Krebs cycle and mitochondria using 3D visualizations and interactive feedback.

Help athletes perform during exercise

Experiment using a mouse model to understand the role of glucose, lactic acid and oxygen during exercise. Apply your knowledge from mouse experiments and of glycolysis, the Krebs cycle and the electron transport chain to help basketball players perform their best during their game.

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