ChIP-exo Virtual Lab
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About the ChIP-exo Virtual Simulation Lab
In the ChIP-exo simulation, you will perform the chromatin immunoprecipitation with exonuclease treatment (ChIP-exo) protocol in order to get a DNA sequence to elucidate the acid stress mechanism of Escherichia coli. You will fix the protein-DNA interactions and lyse the cells using a sonicator, add magnetic beads to the sample and perform different on-bead and off-bead enzymatic modifications, learning how the exonucleases work. Will you be able to prepare the target DNA to understand how E. coli survive in acid stress conditions?
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