Perform the chromatin immunoprecipitation with exonuclease treatment (ChIP-exo) protocol, and prepare the target DNA to learn how E. coli survive in acid stress conditions.
- University / College
About This Simulation
In the ChIP-exo simulation, you will perform the chromatin immunoprecipitation with exonuclease treatment (ChIP-exo) protocol in order to get a DNA sequence to elucidate the acid stress mechanism of Escherichia coli. You will learn how to fix the protein-DNA interactions and lyse the cells using a sonicator, add magnetic beads to the sample, and perform different on-bead and off-bead enzymatic modifications. From this, you will learn how the exonucleases work.
Will you be able to prepare the target DNA to understand how E. coli survive in acid stress conditions?
Explore ChIP-exo Virtual Lab Simulation
How do virtual labs work?
Engage students in science through interactive learning scenarios. Simulate experiments, train lab techniques, and teach theory through visual experiences that enhance long-term learning outcomes.
250+ Web-based simulations that can be played on laptops and tablets without installing any software
Teacher dashboard to automate grading and track student progress
Embedded quizzes to help students master science content
Library of learning resources, lab reports, videos, theory pages, graphics and more
Get started now!
You can explore and assign simulations to your students right away.
- Access to over 250 Labster simulations for free.
- Exclusive educator access to all of Labster Course Manager content.
- 30 days for free, no credit card needed.
- Invite your students to play simulations and get their feedback.
Integrate with your LMS
Labster integrates with all major LMS (Learning Management Systems) so that educators can use their gradebooks to track students’ performance data and students can keep a record of their work.