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Invertebrate Model System

A patient with a deformed head is examined at the hospital. Will you be able to find the mutated protein?
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About This Simulation

A patient with a deformed head is examined at the hospital. You are asked by the doctors to find the genetic defect responsible for this rare condition. Using a model organism, you will perform a forward genetic screen to find its cause. Will you be able to find the mutated protein?

Screenshots

Microscope UV light
View under UV light
Invertebrate Model System workbench
Holographic table model

Collaborators

Prof. Brian Harfe

Prof. Brian Harfe

Associate Dean, College of Liberal Arts and Sciences

University of Florida

Emma Brady

Emma Brady

Senior Instructional Designer

UF Online

Learning Objectives

  • Understanding the importance of C. elegans as an invertebrate model system in medical research
  • Learning how to perform a forward genetic screen
  • Learning how to use sequencing data to discover the genes of interest

Techniques

  • Working with C. elegans
  • Genetic screening
  • Random mutagenesis

Collaborator

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