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About This Simulation
Assist in a biopsy on a cancer patient and learn how to prepare the sample for mass spectrometry by extracting its phosphopeptides. Will you be able to identify the cancer stage of the patient by looking at the phosphorylation pattern?
Learning Objectives
- Understand the correlation between phosphorylation and cancer
- Prepare a biopsy sample for mass spectrometry
About This Simulation
Lab Techniques
- Phosphopeptide enrichment
- Protein purification
- Enzymatic digestion
- Cell lysis
Related Standards
- No direct alignment
- No direct alignment
- No direct alignment
Learn More About This Simulation
Take action! Cancer is on the rise, and you can help with diagnosis and treatment. In the Cancer Sample Preparation for Mass Spectrometry simulation, you will assist doctors by determining the cancer stage of a patient diagnosed with colon cancer. This is the first simulation in the Mass Spectrometry series.
Prepare the biopsy
Join doctors in the hospital and enter an immersive animation to see how we perform a colorectal cancer biopsy. Once back in the lab, your mission will be to extract proteins from the tumor sample. Find the equipment you need in the lab to lyse the tumor cells, denature the proteins, and perform phosphopeptide enrichment, in order to prepare the sample for mass spectrometry.
Explore the molecules
Use the holotable to observe detailed 3D models of the molecules involved in phosphorylation. Get an understanding of the molecular principles underlying the biopsy preparation and how the phosphorylation pattern relates to cancer.
Interpret your findings
In the end, you will analyze the results from the mass spectrometry on a graph. Will you be able to help guide the patient’s treatment by identifying their cancer stage?
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For Science Programs Providing a Learning Advantage
North Dakota State College of Science
“They did the simulation at home, then completed the in-person lab within 30 minutes, no questions asked, and passed the quiz with flying colors.”
Lecturer in Human Physiology
University of Westminster
"I saw some of the students who clearly didn’t necessarily like sitting there reading a book discover they could turn on Labster and keep up with the rest of the class because it spoke to them.
Modesto City Schools
"Having something that's engaging for the students gives teachers that opportunity to breathe and get excited again. Because they're seeing the kids light up, they're seeing the kids engage with content."
Wenatchee Valley College
"The question always is, ‘Can we demonstrate that the students are meeting course outcomes?’ Check! We can do that.”
San José State University
"We surveyed over 400 students. More than 90% thought Labster was easy to navigate, and that it was fun, but more importantly, most of them felt confident that they could execute the labs in person. And that confidence is a big deal."
FAQs
Find answers to frequently asked questions.
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