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About This Simulation
Analyze the microscopic structure of the small intestine and learn the advantages and limitations of light, fluorescence and electron microscopy.
Learning Objectives
- Understand different microscopy techniques and their limitations
- Identify various cell types and cellular structures
- Understand coeliac disease and intestinal inflammation
- Understand staining techniques
About This Simulation
Lab Techniques
- Fluorescence Microscopy
- Light microscopy: using immersion oil and working with different objectives
Related Standards
- Not directly assessed, could support many areas depending on educators approach
- Biology Unit 2: Cell Structure and Function
- 1.1 Introduction to cells*
- 1.2 Ultrastructure of cells
Learn More About This Simulation
Join the Microscopy lab and learn about the different types of microscopy to understand the mechanisms behind it. You will be trained in light microscopy, transmission electron microscopy and fluorescence microscopy.
Use magnification
In the Microscopy lab, you will be presented with chicken intestinal slides that have been stained with Anilin, Orange G and Fuchsin. Using the 5x magnification, you will identify the villus and then proceed with higher magnifications to identify smooth muscle, Relatedcellular tissue, epithelial cells, Goblet cells and the nuclei.
Try out the electron microscope
Electron microscopes can be used to visualize objects that are too small to see when using a light microscope—for example, the microvilli, mitochondria and the junctions between cells. In the Microscopy lab, you will examine a chicken intestine slide that is specially prepared for a transmission electron microscope. You can zoom in and out to observe different cellular structures.
Learn about fluorescence staining techniques
You will learn about fluorescence staining techniques and how they can be used to visualize specific structures. For example, by staining the DNA with DAPI, you can easily identify a cell’s nucleus. In this part of the lab, you will examine a chicken intestine sample that is infected with a retrovirus and observe how the virus infects the lymphocytes and how it inhibits inflammation. The retrovirus can be further developed as a medicine for coeliac disease.
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For Science Programs Providing a Learning Advantage
North Dakota State College of Science
“They did the simulation at home, then completed the in-person lab within 30 minutes, no questions asked, and passed the quiz with flying colors.”
Lecturer in Human Physiology
University of Westminster
"I saw some of the students who clearly didn’t necessarily like sitting there reading a book discover they could turn on Labster and keep up with the rest of the class because it spoke to them.
Modesto City Schools
"Having something that's engaging for the students gives teachers that opportunity to breathe and get excited again. Because they're seeing the kids light up, they're seeing the kids engage with content."
Wenatchee Valley College
"The question always is, ‘Can we demonstrate that the students are meeting course outcomes?’ Check! We can do that.”
San José State University
"We surveyed over 400 students. More than 90% thought Labster was easy to navigate, and that it was fun, but more importantly, most of them felt confident that they could execute the labs in person. And that confidence is a big deal."
FAQs
Find answers to frequently asked questions.
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A Labster virtual lab is an interactive, multimedia assignment that students access right from their computers. Many Labster virtual labs prepare students for success in college by introducing foundational knowledge using multimedia visualizations that make it easier to understand complex concepts. Other Labster virtual labs prepare learners for careers in STEM labs by giving them realistic practice on lab techniques and procedures.
Labster’s virtual lab simulations are created by scientists and designed to maximize engagement and interactivity. Unlike watching a video or reading a textbook, Labster virtual labs are interactive. To make progress, students must think critically and solve a real-world problem. We believe that learning by doing makes STEM stick.
Yes, Labster is compatible with all major LMS (Learning Management Systems) including Blackboard, Canvas, D2L, Moodle, and many others. Students can access Labster like any other assignment. If your institution does not choose an LMS integration, students will log into Labster’s Course Manager once they have an account created. Your institution will decide which is the best access method.
Labster is available for purchase by instructors, faculty, and administrators at education institutions. Purchasing our starter package, Labster Explorer, can be done using a credit card if you are located in the USA, Canada, or Mexico. If you are outside of North America or are choosing a higher plan, please speak with a Labster sales representative. Compare plans.
Labster supports a wide range of STEM courses at the high school, college, and university level across fields in biology, chemistry, physics, and health sciences. You can identify topics for your courses by searching our Content Catalog.