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Mitosis

Dive into the cell cycle phases to understand how cell division occurs. Investigate various types of cells using light and fluorescence microscope to learn the stages of mitosis and how they are regulated.

About This Simulation

Watch an animation and dive into a mammalian cell to learn about eukaryotic DNA packaging. You will perform a series of microscope examination, light and fluorescent, to understand the stages of the cell cycle using mammalian cells and onion root tip cells. Both mitosis and meiosis are types of cell division. In this lab, you will learn the differences between them. Learn about cyclins and cyclin-dependent kinases to understand how the cell cycle is regulated. You will experiment using various cellular parameters and observe the effect of each parameter in the progression of the cell cycle. What does the cell need to be able to divide correctly? In the last part of the lab, you will test the effect of taxol on mammalian cells. From there you will be able to conclude the effect that this plant poison has on cell division. Will the poison inhibit or accelerate cell division? How this affects the survival of the organisms?

Screenshots

Collaborators

Learning Objectives

  • Understanding and visualizing basic concepts about eukaryotic cells such as main cellular components and DNA packaging by immersive animations
  • Learning the key characteristics of the cell cycle´s different stages: interphase (G1, S and G2) and mitosis
  • Using different microscopy techniques to observe the phases of the mitosis and understand their main characteristics:
    • Prophase
    • Metaphase
    • Anaphase
    • Telophase
  • Learning about cell cycle checkpoints and the molecules that control them (cyclins and cyclin-dependent kinases)
  • Understanding the main differences between mitosis and meiosis

Techniques In This Simulation

  • Microscopy

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