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Animal Genetics
Learn about the Mendelian inheritance of double muscling in cattle. Find the responsible gene using linkage analysis and learn how mutation in this gene alters gene expression resulting in double muscled cattle.

About This Simulation

The Animal Genetics Lab guides the student in learning about Mendelian inheritance and how a mutation in the DNA can give rise to an altered phenotype. Students use PCR and gel electrophoresis to perform genotyping in order to discover the gene causing double muscling in cattle.

Screenshots

Collaborators

Prof. Claus Bøttcher Jørgensen

Institute for Department of Basic Animal and Veterinary Sciences

University of Copenhagen

Dr. Camilla Vibeke Sichlau Bruun

Institute for Department of Basic Animal and Veterinary Sciences

University of Copenhagen

Learning Objectives

  • Understanding the different hereditary traits and the modes of inheritance
  • Constructing a pedigree analysis based on observed phenotypes
  • Understanding the genome scanning method to identify candidate genes
  • Identifying the causative gene using various methods
  • Developing a DNA test

Techniques

  • PCR
  • Gel electrophoresis
  • Pedigree/ linkage analysis

Collaborator

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