Ion Exchange Chromatography Virtual Lab

Learn about the function and principles of ion exchange chromatography and get hands-on experience by purifying a protein involved in Parkinson’s disease to help studying the relation between the protein and the disease.

  • University / College

Labster is used by 1000s of amazing schools and universities

Learn more

About This Simulation

This short, targeted simulation is adapted from the full-length Parkinson’s Disease simulation. 

How to purify the protein sample to obtain a high purity compound? Now you have the opportunity to learn one of the techniques that can do that! In the Ion Exchange Chromatography simulation, you will learn what chromatography is and you will perform your own purification experiment.

Prepare the protein sample

First step in chromatography is the preparation of the sample. Therefore, in the beginning you will extract monomers of alpha synuclein (aSN), a protein that is involved in the development of Parkinson’s disease. In order to do so, you will use sonication to extract the protein, which is produced by an E. coli bacterial strain.

Perform ion-exchange chromatography

Next step is the purification of  the extracted aSN monomers by ion exchange chromatography. First, you will learn about the different parts of the chromatography equipment to get familiar with them and then you will apply your knowledge and run the experiment yourself!

Analyze the results and pick the right fraction

Finally, you will analyze the chromatogram and find the fraction that has our purified aSN protein. Your work will help the researchers in their further study. Maybe your contribution will help us find a cure for Parkinon’s disease?

Explore Ion Exchange Chromatography Virtual Lab Simulation

CC1 Screenshot 1
CC1 Screenshot
CC1 Screenshot 3
CC1 Screenshot 4

How do virtual labs work?

Engage students in science through interactive learning scenarios. Simulate experiments, train lab techniques, and teach theory through visual experiences that enhance long-term learning outcomes.

  • 250+ Web-based simulations that can be played on laptops and tablets without installing any software

  • Teacher dashboard to automate grading and track student progress

  • Embedded quizzes to help students master science content

  • Library of learning resources, lab reports, videos, theory pages, graphics and more

Get started now!
You can explore and assign simulations to your students right away.

  • Access to over 250 Labster simulations for free.
  • Exclusive educator access to all of Labster Course Manager content.
  • 30 days for free, no credit card needed.
  • Invite your students to play simulations and get their feedback.
course manager

Integrate with your LMS

Labster integrates with all major LMS (Learning Management Systems) so that educators can use their gradebooks to track students’ performance data and students can keep a record of their work. Labster is compatible with Canvas, Blackboard, Moodle, Google Classroom, Schoology, Sakai, and Brightspace / D2L. It’s also possible to use Labster without an LMS.

Learn more

Related simulations