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About This Simulation
Learn the techniques and application of Polymerase Chain Reaction and Gel Electrophoresis. Explore a real-world application, such as analyzing unique genetic fingerprints to solve a murder case.
Learning Objectives
- Explain the function of DNA polymerase in DNA replication and synthesis
- Perform a PCR experiment using DNA from a blood sample as the template
- Carry out a gel electrophoresis that separates DNA according to its size
- Interpret the unique signature of the human genome and the use of tandem repeated regions (TRR) in DNA profiling
About This Simulation
Lab Techniques
- Gel electrophoresis
- DNA profiling
- Polymerase Chain Reaction (PCR)
Related Standards
- HS-LS1-1, HS-LS3-1
- No direct alignment
- B.4 Medicine
- Biology 3.5 Genetic modification and biotechnology
- 2.7 DNA replication, transcription and translation
Learn More About This Simulation
In the Polymerase Chain Reaction (PCR) simulation, you will be thrown right into a crime scene where a murder has taken place. After investigating the crime scene, your first task is to collect blood samples in the hope that the murderer has left traces of their DNA.
Analyze DNA
After sampling, you will go to the lab to isolate and analyze the sample of DNA you collected. By using a PCR kit, a thermocycler, and the purified DNA from the crime scene, it is up to you to mix the correct reagents and perform the PCR experiment.
See the structure of DNA and its replication up close
A 3D animation will show the PCR experiment at the molecular level, illustrating the structure of DNA and its replication. Quiz questions will be asked throughout the experimental process, as well as at specific steps of the PCR itself.
Identify the murderer
In the PCR simulation, you will look at collected and other prepared samples from the suspects on a gel and then compare the patterns that emerge.
Will you be able to identify the murderer?
Experience Labster for Yourself
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Easily bolster your learning objectives with relevant, interactive content
Practice a lab procedure or visualize theory through narrative-driven scenarios
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For Science Programs Providing a Learning Advantage
North Dakota State College of Science
“They did the simulation at home, then completed the in-person lab within 30 minutes, no questions asked, and passed the quiz with flying colors.”
Lecturer in Human Physiology
University of Westminster
"I saw some of the students who clearly didn’t necessarily like sitting there reading a book discover they could turn on Labster and keep up with the rest of the class because it spoke to them.
Modesto City Schools
"Having something that's engaging for the students gives teachers that opportunity to breathe and get excited again. Because they're seeing the kids light up, they're seeing the kids engage with content."
Wenatchee Valley College
"The question always is, ‘Can we demonstrate that the students are meeting course outcomes?’ Check! We can do that.”
San José State University
"We surveyed over 400 students. More than 90% thought Labster was easy to navigate, and that it was fun, but more importantly, most of them felt confident that they could execute the labs in person. And that confidence is a big deal."
FAQs
Find answers to frequently asked questions.
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Labster is hosted online, which means that students only have to login from their internet browsers once an account is created.
Labster is only available for purchase by faculty and administration at academic institutions. To procure Labster, simply reach out to us on our website. Schedule a demo, book a meeting to discuss pricing, start a free trial, or simply fill out our contact form.
Labster simulations are created by real scientists and designed with unparalleled interactivity. Unlike point and click competitors, Labster simulations immerse students and encourage mastery through active learning.
Labster supports a wide range of courses at the high school and university level across fields in biology, chemistry and physics. Some simulations mimic lab procedures with high fidelity to train foundational skills, while others are meant to bring theory to life through interactive scenarios.