Signal Transduction: How Cells Communicate Virtual Lab

Time to complete course: 24 min.

About the Signal Transduction: How Cells Communicate Virtual Lab Simulation

In this simulation, you will learn how tumor cells send signals to surrounding cells to help promote tumor growth, and how this signal is transmitted inside the cell.

Analyze patient samples by western blotting

As a researcher in the R&D department of a big pharma company, your mission will be to test the hypothesis that increased blood vessel growth, also called angiogenesis, plays a role in breast cancer development. To investigate this idea, you will perform a western blot experiment to test for the expression of vascular endothelial growth factor receptor (VEGFR) expression in patient samples compared to healthy tissue samples.

Learn about VEGFR signal transduction

Following the interpretation of initial results, you will learn more about how VEGFR, a receptor tyrosine kinase (RTK) transmits an external signal to the inside of the cell, and how this influences angiogenesis. You will be able to follow the process in a 3D animation.

Develop a strategy for breast cancer therapy

Finally, your mission is to test different inhibitors targeting VEGFR signaling. You will design an experimental approach to test for the activity of this specific class of RTKs.

Will you be able to identify a promising new drug candidate for treating patients with breast cancer?

Get Started Now

Investigate the connection between blood vessel growth and cancer development, and use this knowledge to identify a promising treatment for breast cancer.

Techniques In Lab

  • Western blotting
  • Cell culture
  • Inhibitor treatment
  • Histology

 

 

Learning Objectives

At the end of this simulation, you will be able to…

  • Explain the principles and importance of intracellular signal transduction
  • Explain receptor tyrosine kinase (RTK) cell signaling
  • Analyze dysregulated signal transduction in human cancer cells
  • Understand the connection between angiogenesis and tumor growth
  • Investigate the involvement of vascular endothelial growth factor receptor (VEGFR) signaling in human breast cancer

Screenshots of Signal Transduction: How Cells Communicate Virtual Lab Simulation

Collaborators

Nina Porakishvili

Department of Biomedical Sciences

Westminster University

Caroline Smith

Department of Life Sciences

Westminster University

How it works

A million dollar lab in your browser

Perform experiments in virtual lab simulations to achieve core science learning outcomes. 

All our simulations run on laptop and desktop computers, and you can play our simulations without having to install any browser plugins.

See detailed minimum requirements here.

Hundreds of hours of science learning content

Our virtual laboratory simulations are aimed at university, college and high school level, within fields such as biology, biochemistry, genetics, biotechnology, chemistry, physics and more.

With access to our simulations, you will have hundreds of hours of engaging, high-quality learning content available to you.

Discover more Virtual Lab Simulations

We currently have 82 simulations that cover everything from biology and medicine to physics and chemistry.

Learn how you can use Labster in your science course