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Simulation Details
Learning Objectives
- Understand the principles and limitations of chemosensitivity testing in the context of in vitro based anticancer drug screening
- Conduct, analyze and interpret in vitro chemosensitivity tests using the MTT assay
- Evaluate the advantages and disadvantages of chemosensitivity tests for in vitro based screening programs
- Prepare cell cultures for chemosensitivity testing
- Determine viable cell numbers using an automated cell counter
- Conduct the MTT assay to assess cell survival following drug exposure
- Generate dose response curves and determine half-maximal effective concentration (EC50) values
- Interpret the results obtained in the chemosensitivity assay
- Understand the mechanisms of action of cyclophosphamide and epirubicin
Skills Developed
Learners practice Laboratory Instruments & Methods, developing skills in performing titration, interpreting NMR, IR, and mass spectrometry results, conducting chromatography and PCR, and carrying out synthetic and sample preparation techniques.
Learners practice Quantitative Reasoning & Scientific Prediction, developing skills in applying algorithmic thinking, using linear and non-linear functions (including logarithmic and trigonometric models), forecasting system states, and implementing Monte Carlo methods.
Learners practice Data Analysis & Graphing, developing skills in data tabulation, creating 2D and 3D graphical representations, identifying patterns, and relating macroscopic trends to microscopic structures.
Lab Techniques
- Cell counting
- EC50 determination
- Drug treatment of cancer cells
- MTT assay
Related Standards
- No direct alignment
- No direct alignment
- No direct alignment
Works With the Tools You Already Use
Labster connects with the systems educators and institutions already rely on. We partner with LMS platforms and leading digital and campus-managed bookstores. Purchase, post assignments, and sync grades without leaving your existing workflows.
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See How Science Programs Are Turning Curiosity Into Action and Mistakes Into Learning
North Dakota State College of Science
“They did the simulation at home, then completed the in-person lab within 30 minutes, no questions asked, and passed the quiz with flying colors.”
University of Westminster
"I saw some of the students who clearly didn’t necessarily like sitting there reading a book discover they could turn on Labster and keep up with the rest of the class because it spoke to them.
Modesto City Schools
"Having something that's engaging for the students gives teachers that opportunity to breathe and get excited again. Because they're seeing the kids light up, they're seeing the kids engage with content."
Wenatchee Valley College
"The question always is, ‘Can we demonstrate that the students are meeting course outcomes?’ Check! We can do that.”
San José State University
"We surveyed over 400 students. More than 90% thought Labster was easy to navigate, and that it was fun, but more importantly, most of them felt confident that they could execute the labs in person. And that confidence is a big deal."
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Frequently Asked Questions
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A Labster virtual lab is an interactive assignment students complete online, on their own schedule. Some labs build foundational knowledge for gateway courses, using visualizations that make complex concepts easier to grasp. Others give students realistic practice with lab techniques and equipment before they step into a wet lab or a STEM career.
Labster supports STEM courses in biology, chemistry, physics, and health sciences within colleges, universities, high school districts, and online academies. Search the Content Catalog to find simulations for your courses.
Yes. Labster integrates with the LMS platforms colleges and universities use most, including Canvas, Blackboard, D2L Brightspace, Moodle, and more. Students open Labster like any other assignment in their course. If your institution doesn't use an LMS integration, students log in through Labster's Course Manager.