Cytogenetics

Students begin this lab in an ultrasound examination room where a young mother-to-be receives an abnormal ultrasound result. Students must find the underlying cause and inform the couple about possible outcomes of their unborn child and future children.

In order to find the underlying cause, students need to perform array CGH using an amniocentesis sample. Students learn the basic principles of array CGH and how to analyze their result. In order to confirm findings, students are required to perform karyotyping for both the fetus and parents. Students learn how to prepare amniocentesis and blood sample for karyotyping and how to analyze their results.

Based on the results and information collected during counseling with the parents; students conclude the underlying cause of the fetus abnormality. Students must explain the fetus’ medical condition and advise the parents in future circumstances.