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About This Simulation
Help a mother-to-be who is extremely worried about the fate of her baby. Will you able to diagnose the condition of the fetus using a cytogenetics-based approach?
Learning Objectives
- Define medical genetic counseling, especially in the case of prenatal diagnostics
- Describe and perform an Array-based Comparative Genome Hybridization (Array CGH)
- Explain a karyotype analysis
About This Simulation
Lab Techniques
- Amniocentesis
- Array comparative genomic hybridization
Related Standards
- No direct alignment
- No direct alignment
- No direct alignment
Learn More About This Simulation
With advances in technology, prenatal diagnosis can provide mothers-to-be with information, not only about the gender of their baby, but also the physical and genetic health. Will you be able to use advanced prenatal techniques to help diagnose a fetal abnormality?
Ultrasound and amniocentesis
In the Cytogenetics simulation, you will begin your mission in an ultrasound examination room where a young mother-to-be receives an abnormal ultrasound result. Your task is to find the underlying cause and to inform her about possible outcomes for her unborn child and any potential future children.
Array comparative genomic hybridization
In order to find the underlying cause of the abnormality, you will perform Array Comparative Genomic Hybridization (Array CGH) using an amniocentesis sample which you isolated previously. You will learn the basic principles of Array CGH and how to analyze the results. In order to confirm your findings, you will also perform karyotyping on both fetal and parental samples. You will learn how to prepare amniocentesis and blood samples for karyotyping, as well as how to analyze the results.
Parent consultation
Based on the results and information collected during the counseling with the parents, you will identify the underlying cause of the fetal abnormality. Your final task is to explain this and the associated medical condition to the mother, before advising her about future risks.
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Cytogenetics: Perform a prenatal diagnosis
Help a mother-to-be who is extremely worried about the fate of her baby. Will you able to diagnose the condition of the fetus using a cytogenetics-based approach?
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For Science Programs Providing a Learning Advantage
North Dakota State College of Science
“They did the simulation at home, then completed the in-person lab within 30 minutes, no questions asked, and passed the quiz with flying colors.”
Lecturer in Human Physiology
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"I saw some of the students who clearly didn’t necessarily like sitting there reading a book discover they could turn on Labster and keep up with the rest of the class because it spoke to them.
Modesto City Schools
"Having something that's engaging for the students gives teachers that opportunity to breathe and get excited again. Because they're seeing the kids light up, they're seeing the kids engage with content."
Wenatchee Valley College
"The question always is, ‘Can we demonstrate that the students are meeting course outcomes?’ Check! We can do that.”
San José State University
"We surveyed over 400 students. More than 90% thought Labster was easy to navigate, and that it was fun, but more importantly, most of them felt confident that they could execute the labs in person. And that confidence is a big deal."
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A Labster virtual lab is an interactive, multimedia assignment that students access right from their computers. Many Labster virtual labs prepare students for success in college by introducing foundational knowledge using multimedia visualizations that make it easier to understand complex concepts. Other Labster virtual labs prepare learners for careers in STEM labs by giving them realistic practice on lab techniques and procedures.
Labster’s virtual lab simulations are created by scientists and designed to maximize engagement and interactivity. Unlike watching a video or reading a textbook, Labster virtual labs are interactive. To make progress, students must think critically and solve a real-world problem. We believe that learning by doing makes STEM stick.
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