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Regeneration Biology

In the Regeneration Biology simulation, you will study regeneration in different vertebrates. Will you be able to figure out why humans cannot regenerate as well as other animals?

About This Simulation

Regeneration is the process of renewal, restoration, and regrowth of tissues, organisms or whole ecosystems. Every species can regenerate. The degree of regeneration, however, varies significantly among different species.

Salamanders are able to regenerate whole limbs. If a Salamander limb is amputated, a blastema forms over the wound. The cells inside the blastema dedifferentiate into multipotent stem cells that remain their positional information. Over the course of weeks, the cells multiply and regenerate a fully functional limb.

Regeneration is often confused with wound healing, but differs significantly. During wound healing, the wound is closed off by forming a scar.

In the Regeneration Biology simulation, you will study regeneration in different vertebrates. Amputate the limb of a salamander and observe how the whole limb regenerates!
Will you be able to figure out why humans cannot regenerate as well as other animals?

Screenshots

Collaborators

Prof. Malcolm Maden

Prof. Malcolm Maden

Biology department

University of Florida

Prof. Brian Harfe

Prof. Brian Harfe

Associate Dean, College of Liberal Arts and Sciences

University of Florida

Emma Brady

Emma Brady

Senior Instructional Designer

UF Online

Learning Objectives

  • Learning that the ability to regenerate tissues varies throughout vertebrates
  • Understanding what a blastema is and the cell types that compose this structure
  • Understanding the concept of positional information in regeneration

 

Techniques

Collaborator

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