Signal Transduction: Choose the best cancer inhibitor
Investigate the connection between blood vessel growth and cancer development. Use this knowledge to help the pharma company in their quest to uncover promising drug candidates to treat breast cancer patients.
- University / College
About This Simulation
This shorter, targeted simulation is adapted from the full-length “Signal Transduction” simulation.
How do tumors promote their growth in the human body? In this simulation, you will learn how tumor cells send signals to surrounding cells to help promote tumor growth, and how this signal is transmitted inside the cell. You will help a big pharma company uncover the most effective inhibitor to cancerous cell growth and therefore, a promising new drug candidate to treat breast cancer patients.
Analyze patient samples by western blotting
As a researcher in the R&D department of a big pharma company, your mission will be to test the hypothesis that increased blood vessel growth, also called angiogenesis, plays a role in breast cancer development. To investigate this idea, you will interpret the results of a western blot experiment to test for the expression of vascular endothelial growth factor receptor (VEGFR) expression in patient samples compared to healthy tissue samples.
Learn about VEGFR signal transduction
Following the interpretation of initial results, you will learn more about how VEGFR, a receptor tyrosine kinase (RTK) transmits an external signal to the inside of the cell, and how this influences angiogenesis. You will be able to follow the process in a 3D animation.
Develop a strategy for breast cancer therapy
Finally, your mission is to test different inhibitors targeting VEGFR signaling. You will design an experimental approach to test for the activity of this specific class of RTKs. Report back to the company with your key findings! Will you be able to identify a promising new drug candidate for treating patients with breast cancer?
Explore Signal Transduction: Choose the best cancer inhibitor Virtual Lab Simulation
How do virtual labs work?
Engage students in science through interactive learning scenarios. Simulate experiments, train lab techniques, and teach theory through visual experiences that enhance long-term learning outcomes.
250+ Web-based simulations that can be played on laptops and tablets without installing any software
Teacher dashboard to automate grading and track student progress
Embedded quizzes to help students master science content
Library of learning resources, lab reports, videos, theory pages, graphics and more
Get started now!
You can explore and assign simulations to your students right away.
- Access to over 250 Labster simulations for free.
- Exclusive educator access to all of Labster Course Manager content.
- 30 days for free, no credit card needed.
- Invite your students to play simulations and get their feedback.
Integrate with your LMS
Labster integrates with all major LMS (Learning Management Systems) so that educators can use their gradebooks to track students’ performance data and students can keep a record of their work.